What
is clinical depression?
Clinical
depression is more than the typical feelings of sadness that
occur in response to negative events. Clinical depression includes emotional,
cognitive (thinking), physical and behavioral symptoms that last longer
than two weeks. Emotional symptoms include sadness, irritability and
anxiety, as well as decreased enjoyment and interest. Cognitive symptoms
include ideas of worthlessness, helplessness and hopelessness, as well
as difficulty with concentration and memory. Hopelessness can lead to
suicidal thoughts, plans and attempts. Physical symptoms, such as decreased
energy and sleep/appetite changes, can initially be mistaken for a general
medical condition. Behavioral symptoms include crying, irritable behavior,
social withdrawal and decreased activity and productivity.
Clinical
depression can present with varying degrees of severity and length.
It is a common illness that causes marked distress and interferes with
relationships and work functioning. Clinical depression affects people
of all ages, women more than men. There is some evidence that clinical
depression, if left untreated, may complicate or worsen general medical
conditions such as heart disease.
We are currently conducting several studies evaluating the effectiveness of medications on treating major depression. Participants will receive a psychiatric evaluation, a physical exam, laboratory tests, and study medication at no cost.