Dr. Andrew Miller is William P. Timmie Professor of Psychiatry and
Behavioral Sciences and Director of Psychiatric Oncology at the Winship
Cancer Institute at the Emory University School of Medicine in Atlanta,
Georgia. He is an internationally recognized leader in the area of
brain-immune interactions as they relate to stress and depression.
His work focuses on the mechanisms by which cytokines cause depression
in humans and non-human primates using chronic administration of the
innate immune cytokine, interferon-alpha, as a model of chronic immune
stimulation. Dr. Miller's work has shown that during chronic interferon-alpha
treatment, cytokines access the brain and interact with the metabolism of
relevant neurotransmitters including serotonin and dopamine. He has also
shown that cytokines alter neurocircuits in the brain relevant to motivation
and reward as well as anxiety and alarm. In addition, Dr. Miller has
studied the impact of cytokines on neuroendocrine regulation as well
as sleep including the study of specific signal transduction pathways
that may be involved such as NF-kB and p38 mitogen activated protein kinase.
Finally, Dr. Miller and his group are currently conducting clinical trials
examining the efficacy of cytokine antagonists in patients with treatment
Dr. Miller has produced over 200 scholarly publications and edited a book
entitled Depressive Disorders and Immunity. Dr. Miller's research awards
include the Curt Richter Award from the International Society of
Psychoneuroendocrinology and the Norman Cousins Award from the Psychoneuroimmunology
Research Society. Aside from his research endeavors, Dr. Miller is a Board
Certified Psychiatrist and past examiner for the American Board of Psychiatry and Neurology.